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Principles of Nucleotide Activity

PHA 6535 Principles of Nucleotide Activity

Credits: 2


This course will introduce students to the chemical structure of DNA and RNA; the synthetic processes for DNA and RNA synthesis; biochemical reactions and pathways for nucleotide synthesis; DNA replication, transcription and translation; covalent and reversible interactions of nucleic acids with small molecules and proteins and an overview of techniques for the analysis of nucleic acids.


Please review our recommended course order.


Module Topic
Module 1 DNA and RNA Structure
Module 2 DNA Packaging, Replication, Repair, and Recombination
Module 3 RNA Sequence Information
Module 4 Nucleotide Biosynthesis
Module 5 The Role of Nucleotides in Protein Synthesis and Protein-Nucleic Acid Interactions
Module 6 Reversible and Covalent Interactions of Nucleic Acids with Small Molecules
Module 7 Chemical Synthesis
Module 8 Techniques Applied to Nucleic Acids

Required Materials

Lehninger Principles of Biochemistry 7th Edition
by David L. Nelson, Michael M. Cox
Publisher: MacMillan Learning; 7th edition (2017)
ISBN-13: 978-1464126116
ISBN-10: 1464126119

Please note: this is the same text that is required for Metabolic Biochemistry, PHA 6935

Library Access

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